Melanonychia

What is Melanonychia?

The word “melanonychia” comes from Greek:

“Melas” = black or brown

“Onyx” = nail

Melanonychia means a dark brown or black line (or band) that appears on the nail. It happens when pigment (melanin) collects in the nail plate. The line can be thin or wide, can affect one nail or several nails, and it may appear on both fingernails and toenails.

Why does Melanonychia happen?

Melanonychia occurs because of changes in melanocytes (the cells that make melanin, the pigment that gives color) become active. There are two main ways this happens:

  • Melanocytic activation – the number of melanocytes stays the same, but they produce more melanin.

  • Melanocytic hyperplasia – the number of melanocytes increases. This can be benign (harmless) or sometimes malignant (linked to nail melanoma).

What can cause melanonychia?

Causes of melanocytic activation:

  • Racial differences – More common in people with darker skin

  • Pregnancy – Hormonal changes may cause streaks in multiple nails.

  • Fungal infections – Some fungi make melanin that gets into the nail.

  • Bacterial infections – Especially in people with weak immunity

  • Viral infections – People with HIV may develop nail streaks.

  • Skin conditions – Psoriasis, lichen planus, amyloidosis.

  • Trauma – Nail biting, chewing, friction, or repeated injury.

  • Tumors – Both benign and malignant.

  • Systemic diseases – Addison’s disease, Cushing’s syndrome (often multiple nails affected).

  • Drugs – Certain medications can cause transverse (horizontal) streaks.

  • Medical treatments – Chemotherapy, radiation, or X-rays may trigger changes.

Note: Many causes are harmless, but melanonychia can also be a sign of nail melanoma, especially if the band is irregular, widening, or only in one nail.

What are the types of melanonychia?

There are three main types:

  • Longitudinal melanonychia (melanonychia striata):

    • The most common type.

    • Appears as a long, narrow band running from the cuticle to the tip of the nail.

  • Diffuse or total melanonychia:

    • The entire nail plate looks dark or discolored.

  • Transverse melanonychia:

    • A horizontal band of color that runs across the width of the nail.

Is melanonychia dangerous?

Not always. Many cases are harmless, especially if seen in multiple nails or in people with darker skin. But if the line appears suddenly, changes shape, widens, or is only on one nail — it needs to be checked urgently because it can sometimes be a sign of melanoma.

What are the warning signs to look for?

Contact a dermatologist if you notice any of these:

  • A new dark line or streak on a nail (especially if it affects only one nail).

  • The band becoming wider, darker, or changing shape over time.

  • Irregular or blurred borders of the streak.

  • Nail changes such as cracking, bleeding, or pain.

  • Dark pigment spreading to the surrounding skin (known as Hutchinson’s sign).

  • A band that is wider than 1/8 inch (3 mm).

How is melanonychia diagnosed?

A dermatologist will:

Medical history & nail exam

  • The doctor first asks about your health, medications, and any history of trauma or illness.

  • They then check how many nails are affected, and look at the pattern, color, and shape of the dark streaks.

Onychoscopy (special nail microscope test)

  • The doctor may use a tool called a dermatoscope to look at your nail closely.

  • This helps them tell melanonychia apart from other conditions:

    • For example, a splinter hemorrhage (tiny blood clot under the nail) looks like a reddish-brown streak, but it’s different from melanonychia.

Biopsy (for confirmation)

  • If the doctor suspects something serious like nail melanoma, they may do a biopsy.

  • This means removing a small part of the nail or nail bed and checking the cells under a microscope.

  • A biopsy is the gold standard (most accurate test) for confirming whether the streak is benign (harmless) or malignant (cancerous).

How is it treated?

Benign causes (harmless streaks)

  • If the streak is not dangerous, treatment may not be needed.

  • Medication-related: If a medication caused the discoloration, the streak often fades within 6–8 weeks after stopping that medicine.

  • Infections: Treated with antifungal or antibacterial medicines.

Malignant causes (nail melanoma)

  • If the melanonychia is due to nail unit melanoma (NUM), treatment is more serious.

  • A doctor may recommend surgery, which could involve:

    • Removing the entire nail unit.

    • In severe cases, amputating the tip of the finger or toe to stop the spread of cancer.

Can melanonychia be prevented?

Not always. But protecting nails from repeated trauma (like tight shoes), avoiding unnecessary medications, and regular nail checks help.

Myths vs Facts About Melanonychia

  • Myth 1: Every black line on the nail is cancer.

    Fact: Most dark lines are harmless and caused by things like injury, medicines, or natural skin color. Only a small percentage are linked to melanoma.

  • Myth 2: If the line doesn’t hurt, it can’t be serious.

    Fact: Nail melanoma often doesn’t cause pain in the beginning. A painless but changing line can still be dangerous.

  • Myth 3: Melanonychia happens only in older people.

    Fact: It can occur at any age — children, young adults, and older people. However, melanoma is more common in adults.

  • Myth 4: If the line is on many nails, it must be cancer.

    Fact: Melanoma usually affects one nail. Lines on multiple nails are more often harmless (racial pigmentation, medication, or systemic conditions).

  • Myth 5: You can tell if it’s cancer just by looking at it at home.

    Fact: Only a dermatologist can confirm the cause — sometimes with a biopsy. Self-diagnosis can be misleading and risky.

  • Myth 6: Cutting or scraping the nail will remove it.

    Fact: Since the pigment is inside the nail, trimming won’t make it disappear.

  • Myth 7: Home remedies can cure melanonychia.

    Fact: No oil, cream, or home trick can remove the pigment. The cause needs to be identified by a doctor.

  • Myth 8: It’s just dirt under the nail.

    Fact: Melanonychia is pigment inside the nail plate, not dirt that can be cleaned off.

Final Thought:

Melanonychia is not just “one cause” — it can come from skin tone, infections, trauma, systemic diseases, or even medications. Most cases are harmless, but any sudden, single-nail, or changing dark line must be checked by a dermatologist to rule out melanoma.

Disclaimer: This article is only for general patient information and is not intended for self medication. There is no legal liability of IADVL arising out of any adverse consequence to the patient. Subsequent to its use for self treatment of the disease images adjust for the depiction of the condition and is not to be used for any other purpose.